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Depression after traumatic brain injury may not be the same as depression from other causes: study

Published Sat, 22 Feb 2025 14:47:31 GMT

A new study suggests that depression after traumatic brain injury may not be the same as depression related to other causes, according to researchers from Brigham and Women’s Hospital.The study of 273 people found that brain circuits associated with depression were different between people with traumatic brain injury (TBI) and those without TBI.“Our findings help explain how the physical trauma to specific brain circuits can lead to development of depression,” said study leader Shan Siddiqi, of the Brigham’s Department of Psychiatry and Center for Brain Circuit Therapeutics.“If we’re right, it means that we should be treating depression after TBI like a distinct disease,” Siddiqi added. “Many clinicians have suspected that this is a clinically distinct disorder with a unique pattern of symptoms and unique treatment response, including poor response to conventional antidepressants — but until now, we didn’t have clear physiological evidence to prove this.”The study included 273 adult...

Chipotle’s Pizzeria Locale closing all locations, dissolving the business

Published Sat, 22 Feb 2025 14:47:31 GMT

Pizzeria Locale, once a promising and popular joint venture between a local restaurant group and the Chipotle chain, announced Wednesday that it will close its remaining locations.“We have made the decision to close all five Pizzeria Locale restaurants on July 10 and dissolve the business,” Chipotle chief corporate affairs officer Laurie Schalow said in a statement. “Impacted employees have been extended employment opportunities at Chipotle restaurants in the Denver area.”The move, first reported by Westword, comes six months after Pizzeria Locale founders Bobby Stuckey and Lachlan Mackinnon-Patterson separated their original location, a sit-down restaurant at 1738 Pearl St. in Boulder, from Pizzeria Locale’s fast-casual spots, by rebranding it as Pizzeria Alberico.Stuckey and Mackinnon-Patterson, who are also behind Frasca, Tavernetta and Sunday Vinyl, founded Pizzeria Locale in 2010 and struck up a partnership with Chipotle in 2013. The goal at the time was to rapidly expand in a ...

Warrant issued for suspect in fatal Richmond hit-and-run

Published Sat, 22 Feb 2025 14:47:31 GMT

RICHMOND — Investigators have identified a suspect and secured an arrest warrant for a driver they believe fatally hit a bicyclist last week on Richmond Parkway, police said.Authorities identified the bicyclist as 60-year-old David Sexton, of San Francisco. He was dead when officers arrived to the Richmond Parkway at Goodrick Avenue about 10 p.m. July 1.Richmond police spokesperson Sgt. Donald Patchin said the vehicle that hit the bicyclist kept going after the collision. Authorities have obtained a arrest warrant for a felony hit-and-run and vehicular manslaughter, he said.Witness statements after the crash allowed investigators to identify the vehicle. Patchin said they later found it abandoned in San Pablo with damage matching the suspect vehicle as described by witnesses.“We know that speed is a factor in this,” Patchin said. “It is unknown whether alcohol or drugs were a factor.”Police did not give any information about the vehicle or identify the ...

Silicon Valley startup’s flying car prototype just got an airworthiness certificate from the FAA

Published Sat, 22 Feb 2025 14:47:31 GMT

New York — The Federal Aviation Administration has certified for testing a vehicle that a San Mateo, California startup describes as a flying car — the first fully electric vehicle that can both fly and travel on roads to receive US government approval.Alef Automotive said that its vehicle/aircraft, dubbed the “Model A,” is the first flying vehicle that is drivable on public roads and able to park like a normal car. It also has vertical takeoff and landing capabilities. It apparently will be able to carry one or two occupants and will have a road-range of 200 miles and a flying range of 110 miles.The company expects to sell the vehicle for $300,000 each with the first delivery by projected for the end of 2025.The FAA confirmed that it has issued the company a special airworthiness certificate, allowing for limited purposes that include exhibition, research and development.Numerous companies are working on all-electric VTOLs, which stands for vehicle takeoff and landing aircraft. The...

Rep. Schiff, censured by GOP, raises $8.1 million for senate race

Published Sat, 22 Feb 2025 14:47:31 GMT

By Michael R. Blood | Associated PressLOS ANGELES — U.S. Rep. Adam Schiff’s Senate campaign said Wednesday that the California Democrat had raised $8.1 million over the past three months, a period that includes his recent censure by the Republican-led House.His team said that was a record for a Senate campaign for the April-through-June quarter of a year in which an election is not taking place. The 2024 race is to fill the seat of retiring Democratic Sen. Dianne Feinstein.However, federal records show that Majority Leader Chuck Schumer’s main campaign committee raised over $11 million in the second quarter of 2021, a year when he was not facing reelection.Schiff’s campaign said in the announcement that the $8.1 million amount represented “the most any Senate campaign nationwide has raised in Q2 of an off-cycle year, ever.” Campaign communications director Marisol Samayoa said in an email the “record” amount referred to fundraising in open S...

Parolee arrested in connection to daytime shooting in downtown San Rafael

Published Sat, 22 Feb 2025 14:47:31 GMT

(KRON) -- A 31-year-old San Rafael man who was already on parole was arrested last week in connection to a daytime shooting in downtown San Rafael, the San Rafael Police Department said. Marco Antonio Gramajo was arrested on Thursday, June 29 at his home on the 100 block of Andersen Drive in San Rafael.The arrest stemmed from incidents that began around 3 p.m. on Saturday, June 24. San Rafael PD officers responded to 911 calls about a fight near Fourth and D streets in downtown San Rafael. At the scene, officers were unable to locate a fight. Cruise ship visibly damaged after hitting SF pier while docking However, a short while later, an officer driving on Fourth was waived down by someone who had witnessed the fight. The witness told the officer that a suspect involved in the fight, later identified as Gramajo, had fired a gun at a victim who was no longer on the scene. The officer investigated where the witness said the shooting occurred and found a spent shell casing and an int...

TikTok and 5 content creators ask federal judge to block Montana from banning app

Published Sat, 22 Feb 2025 14:47:31 GMT

TikTok Inc. and a group of five content creators who are suing the state of Montana over its first-in-the-nation law to ban the video sharing app are now asking a federal judge to block implementation of the law while the case moves through the courts and before it takes effect in January.The separate requests for preliminary injunctions were filed Wednesday in federal court in Missoula. The cases challenging the law were filed in May and have since been consolidated by U.S. District Judge Donald Molloy. Montana Attorney General Austin Knudsen had the bill drafted over concerns — shared by the FBI and U.S. Secretary of State Antony Blinken — that the app, owned by the Chinese company ByteDance, could be used to allow the Chinese government to access information on U.S. citizens or push pro-Beijing misinformation that could influence the public. TikTok has said none of this has ever happened.The motions for injunctions make the same arguments as the cases against the state — that the...

Made in HimmerLand Par Scores

Published Sat, 22 Feb 2025 14:47:31 GMT

ThursdayAt Himmerland Golf & Spa ResortFarsoPurse: $3.3 millionYardage: 6,647; Par: 70First RoundRobert Macintyre, Scotland33-31—64-6Ross Fisher, England33-33—66-4Nick Bachem, Germany34-33—67-3Daan Huizing, Netherlands33-34—67-3Johannes Veerman, United States33-34—67-3Lucas Bjerregaard, Denmark33-35—68-2Rasmus Hojgaard, Denmark35-33—68-2Alexander Levy, France34-34—68-2Andy Sullivan, England33-35—68-2Daniel Brown, England36-33—69-1Nacho Elvira, Spain35-34—69-1Ryo Hisatsune, Japan36-33—69-1Matthieu Pavon, France35-34—69-1David Ravetto, France35-34—69-1Todd Clements, England36-34—70EJeremy Freiburghaus, Switzerland36-34—70EMateusz Gradecki, Poland35-35—70EKristian Krogh Johannessen, Norway34-36—70EFrederik Kjettrup, Denmark33-37—70ERichard Mansell, England36-34—70EEddie Pepperell, England35-35—70ERichie Ramsay, Scotland34-36—70EBrandon Robinson-Thompson, England33-37—70EAdrien Saddier, France35-35—70EMarc Warren, Scotland36-34—70EGunner Wiebe, United States36-34—70EJeff Winther, De...

Tigers to get back Faedo, their 3rd starting pitcher in 4 days, on Friday

Published Sat, 22 Feb 2025 14:47:31 GMT

DETROIT (AP) — Detroit Tigers starter Alex Faedo will come off the 15-day injured list to pitch against the Toronto Blue Jays on Friday.Faedo has been sidelined since May 31 with discomfort in his right middle finger. After a procedure to remove the fingernail, he made a rehab start for Single-A West Michigan on Sunday. He allowed four runs on six hits and a walk in 3 1/3 innings.Faedo will be the third Tigers starter to return in four days. Tarik Skubal (elbow) made his season debut on Tuesday, pitching four hitless innings, while Eduardo Rodriguez (finger) allowed five runs in four innings on Wednesday. The Tigers lost both games to the Oakland Athletics.Faedo, 27, is 1-3 with a 5.54 ERA in five starts this season.Tigers outfielders Akil Baddoo (quad strain) and Riley Greene (leg) could also return during the Toronto series.___AP MLB: https://apnews.com/hub/mlb and https://twitter.com/AP_SportsSource

Backers of effort to repeal Alaska’s ranked voting system accused of campaign finance violations

Published Sat, 22 Feb 2025 14:47:31 GMT

ANCHORAGE, Alaska (AP) — Backers of an effort to repeal Alaska’s ranked choice voting system violated campaign finance rules and obscured the source of their funding, including forming a church that could have allowed donors to gain tax advantages for their contributions while skirting disclosure mandates, a complaint alleges.The complaint was filed by Alaskans for Better Elections, which was behind the successful 2020 ballot measure that replaced party primaries with open primaries and instituted ranked choice voting for general elections. The complaint is lodged against several individuals and groups involved in the repeal effort, including Art Mathias and Phillip Izon, the Anchorage Daily News reported.A group called Alaskans for Honest Elections has been gathering signatures in support of a ballot measure that seeks to repeal the new voting system. The Ranked Choice Education Association is the primary contributor to the group. But the complaint alleges the association was...